![]() ![]() ![]() FDA requiring Boxed Warning updated to improve safe use of benzodiazepine drug class.drug-topics/opioids/benzodiazepines-opioids You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. ![]() For a more complete list, see the interactions for diazepam and interactions for alprazolam.Īlways tell your doctor and pharmacist about all drugs and supplements you currently take before you start taking any new drug. These are not all of the possible drug interactions. antidepressants, mood stabilizers, and antipsychotics.pain drugs, including hydrocodone, oxycodone, methadone, codeine, and tramadol.other benzodiazepines or sedatives, such as sleeping pills and drugs for anxiety.That’s because they can affect your respiratory system. Medications that affect your central nervous system can be dangerous when combined with benzodiazepines. Xanax and Valium are in the same drug class, so they have many of the same interactions with other drugs and substances. This can increase your risk of side effects. So having large amounts of grapefruit can increase the levels of Valium and Xanax in your body. Grapefruit blocks the enzyme CYP3A4, which helps break down certain drugs. If you take Valium or Xanax, you should avoid large amounts of grapefruit or grapefruit juice. ![]()
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